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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CKM
All Species:
44.85
Human Site:
S199
Identified Species:
70.48
UniProt:
P06732
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06732
NP_001815.2
381
43101
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Chimpanzee
Pan troglodytes
XP_001163660
381
42901
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001112108
381
42634
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Dog
Lupus familis
XP_533641
488
54723
S306
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
P07310
381
43026
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Rat
Rattus norvegicus
P07335
381
42707
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508143
326
36755
K187
L
R
V
I
S
M
Q
K
G
G
N
M
K
E
V
Chicken
Gallus gallus
P00565
381
43310
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Frog
Xenopus laevis
NP_001080073
381
42887
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
A
G
Zebra Danio
Brachydanio rerio
NP_571007
381
42806
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48610
356
39848
R193
F
L
F
K
E
G
D
R
F
L
Q
A
A
N
A
Honey Bee
Apis mellifera
O61367
355
39990
Q195
K
E
G
D
R
F
L
Q
A
A
N
A
C
R
F
Nematode Worm
Caenorhab. elegans
Q27535
360
40364
R197
F
L
F
K
E
G
D
R
F
L
K
A
A
N
A
Sea Urchin
Strong. purpuratus
P18294
1174
130851
S613
F
L
F
D
K
P
V
S
P
L
L
T
A
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001169054
381
42707
S199
F
L
F
D
K
P
V
S
P
L
L
L
A
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
80.5
75.1
N.A.
96.5
79.5
N.A.
70.3
90.2
88.7
88.7
N.A.
42.5
40.4
37.5
22.4
Protein Similarity:
100
97.3
90.2
77.4
N.A.
98.9
89.5
N.A.
78.2
95.8
95.5
94.2
N.A.
58.7
59
55.3
27.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
93.3
93.3
N.A.
33.3
6.6
33.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
46.6
20
46.6
86.6
Percent
Protein Identity:
N.A.
79.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
89.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
100
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
7
0
20
87
20
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
0
0
0
80
0
0
14
0
0
0
0
0
0
0
0
% D
% Glu:
0
7
0
0
14
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
87
0
87
0
0
7
0
0
14
0
0
0
0
0
7
% F
% Gly:
0
0
7
0
0
14
0
0
7
7
0
0
0
0
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
0
0
14
74
0
0
7
0
0
7
0
7
0
0
% K
% Leu:
7
87
0
0
0
0
7
0
0
87
74
67
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
14
0
0
14
0
% N
% Pro:
0
0
0
0
0
74
0
0
74
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
0
% Q
% Arg:
0
7
0
0
7
0
0
14
0
0
0
0
0
7
7
% R
% Ser:
0
0
0
0
7
0
0
74
0
0
0
0
0
54
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
7
0
0
0
74
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _